Fig. 2

Effects of dapagliflozin administration on metabolic parameters in lean and ob/ob mice. Effects of dapagliflozin on blood glucose levels and weight trend analysis after treatment. After 30 days of treatment, a significant reduction of blood glucose plasma levels was observed in both lean and ob/ob animals treated with dapagliflozin. Body weight reduction was reported in both lean and ob/ob mice; however, the statistical significance was observed only in the treated lean group