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Fig. 4 | BMC Endocrine Disorders

Fig. 4

From: The effects of SGLT2 inhibitors on metabolic phenotype and FGF-21 expression from the adipose tissue and the liver are less pronounced in ob/ob mice

Fig. 4

Effects of dapagliflozin administration on markers of BAT activation. Considering the potential modulation of FGF-21 on thermogenesis markers of BAT activation (UCP-1, PGC-1α, CIDEA) were evaluated. Of note, dapagliflozin treatment significantly increased mRNA expression of UCP-1 in lean animals but not in ob/ob mice (*p < 0.05)

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BMC Endocrine Disorders

ISSN: 1472-6823

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