Association of estimated small dense low-density lipoprotein cholesterol with diabetes mellitus: a large-scale multicenter retrospective cohort study

Table 4 Relationship between sdLDL-C and incident diabetes in different models

Exposure	Model 1 (HR.,95% CI, P)	Model 2 (HR,95% CI, P)	Model 3 (HR,95% CI, P)
sdLDL-C	1.04 (1.04, 1.04) < 0.0001	1.02 (1.02, 1.02) < 0.0001	1.04 (1.03, 1.04) < 0.0001
sdLDL-C (quartile)
Q1	Ref	Ref	Ref
Q2	2.56 (2.17, 3.02) < 0.0001	1.58 (1.34, 1.87) < 0.0001	1.69 (1.43, 2.01) < 0.0001
Q3	4.34 (3.71, 5.07) < 0.0001	1.80 (1.54, 2.12) < 0.0001	2.09 (1.76, 2.48) < 0.0001
Q4	7.07 (6.09, 8.21) < 0.0001	2.27 (1.94, 2.65) < 0.0001	2.94 (2.44, 3.55) < 0.0001
P for trend	< 0.0001	< 0.0001	< 0.0001

Model 1: we did not adjust for any covariants
Model 2: we adjusted for gender, age, SBP, DBP, family history of diabetes, drinking status, smoking status, and BMI
Model 3: we adjusted for gender, age, SBP, DBP, family history of diabetes, drinking status, smoking status, BMI, HDL-C, TC, ALT, AST, Scr, BUN, and FPG
sdLDL-C: estimated small dense low-density lipoprotein cholesterol; HR: hazard ratios; CI: confidence interval; Ref: reference

ISSN: 1472-6823