Association of estimated small dense low-density lipoprotein cholesterol with diabetes mellitus: a large-scale multicenter retrospective cohort study

Table 5 Relationship between sdLDL-C levels and incident diabetes in different sensitivity analyses

Exposure	Model 4 (HR,95%CI, P)	Model 5 (HR,95%CI, P)	Model 6 (HR,95%CI, P)
sdLDL-C	1.04 (1.03, 1.05) < 0.0001	1.04 (1.03, 1.05) < 0.0001	1.04 (1.04, 1.05) < 0.0001
sdLDL-C (quartile)
Q1	Ref	Ref	Ref
Q2	1.61 (1.24, 2.09) 0.0004	1.53 (1.25, 1.88) < 0.0001	1.67 (1.34, 2.08) < 0.0001
Q3	2.14 (1.64, 2.81) < 0.0001	2.01 (1.64, 2.47) < 0.0001	2.24 (1.80, 2.78) < 0.0001
Q4	3.02 (2.21, 4.14) < 0.0001	2.92 (2.32, 3.68) < 0.0001	3.17 (2.47, 4.07) < 0.0001
P for trend	< 0.0001	< 0.0001	< 0.0001

Model 4 was sensitivity analysis in participants without BMI ≥ 24 kg/m². We adjusted gender, age, SBP, DBP, family history of diabetes, drinking status, smoking status, BMI, HDL-C, TC, ALT, AST, Scr, BUN, and FPG
Model 5 was sensitivity analysis in participants without SBP ≥ 140 or DBP ≥ 90 mmHg. We adjusted gender, age, SBP, DBP, family history of diabetes, drinking status, smoking status, BMI, HDL-C, TC, ALT, AST, Scr, BUN, and FPG
Model 6 was sensitivity analysis in participants without FPG ≥ 6.1 mmol/L. We adjusted gender, age, SBP, DBP, family history of diabetes, drinking status, smoking status, BMI, HDL-C, TC, ALT, AST, Scr, BUN, and FPG
sdLDL-C: estimated small dense low-density lipoprotein cholesterol; HR, hazard ratios; CI, confidence, Ref: reference

ISSN: 1472-6823