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Table 5 Adjusted MD (%95CI) and adjusted SMD (%95CI) for biomarkers of fatty liver

From: The effect of empagliflozin on non-alcoholic fatty liver disease-related parameters in patients with type 2 diabetes mellitus: a randomized controlled trial

  

Intervention (N = 69)

Control (N = 50)

  

Mean (SD)

MD (95%CI)

SMD (%95CI)

ALT*

Baseline

71.33 (49.35)

47.52 (7.46)

-

-

Month 3

41.48 (2.12)

43.46 (1.08)

-6.58 (-11.35, -1.82)

-0.47 (-0.84, -0.1)

Month 6

30.16 (1.33)

42.9 (1.12)

-15.33 (-18.8, -11.88)

-1.73 (-2.16, -1.31)

AST*

Baseline

46.74 (14.14)

42.54 (11.61)

-

-

Month 3

35.65 (1.24)

39.42 (1.46)

-5.97 (-8.83, -3.1)

-0.6 (-0.96, -0.22)

Month 6

28.34 (0.99)

39.2 (1.54)

-12.82 (-15.5, -10.13)

-1.46 (-1.86, -1.05)

ALKp*

Baseline

186.91 (66.43)

197.98 (40.30)

-

-

Month 3

176.52 (7.32)

195.34 (5.53)

-10.28 (-2.2, 0.63)

-0.19 (-0.55, 0.17)

Month 6

183.12 (7.67)

196.8 (5.57)

-4.1 (-13.08, 4.88)

-0.07 (-0.44, 0.29)

GGT*

Baseline

59.s55 (26.09)

42.07 (9.52)

-

-

Month 3

41.91 (19.90)

42.68 (11.70)

-9.36 (-14.34, -4.38)

-0.74 (-1.11, -0.36)

Month 6

34.01 (14.80)

41.48 (10.82)

-15.58 (-18.68, -12.47)

-1.97 (-2.41, -1.52)

SBP**

Baseline

118.19 (11.42)

120.86 (9.10)

-

-

Month 3

115.62 (11.34)

120.60 (8.61)

-2.84 (-5.26, -0.42)

-0.43 (-0.80, -0.7)

Month 6

112.32 (10.73)

120.70 (8.81)

-6.31 (-8.65, -3.97)

-0.87 (-1.25, -0.5)

  1. *Adjusted MD and SMD for baseline measurement using multiple linear regression
  2. ** Adjusted SMD for baseline measurement and BMI change using multiple linear regression