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Table 2 The linear correlations between the SAR with BMDs and an individualized 10-year probability of MOF and HF were estimated through Spearman’s partial correlation analysis

From: Systemic immune-inflammation index to albumin (SII/ALB) ratio as a novel dual-dimensional powerful predictor for hip fractures in elderly females with diabetes: a postmenopausal longitudinal cohort study

 

LS - BMD

FN - BMD

TH - BMD

MOF

HF

r

p

r

p

r

p

r

p

r

p

Model I

-0.090

0.088

-0.151

0.004*

-0.163

0.002*

0.177

<0.001*

0.174

<0.001*

Model II

-0.068

0.198

-0.108

0.041*

-0.118

0.025*

0.136

0.010*

0.139

0.008*

Model III

-0.013

0.815

0.030

0.579

-0.025

0.652

0.065

0.236

0.070

0.201

  1. Notes: Model I: adjusted for none. Model II: adjusted for age and duration of diabetes. Model III: adjusted for age, duration of diabetes, hypertension, DPN, PVD, BMI, FBG, HbA1c, Hb, TSH, FT3, FT4, TC, TG, HDL-C, LDL-C, Cr, UA, Ca, 25(OH) D, WBC, Neut, Plt, Lym, ALB, osteoporosis, fracture history. * P < 0.05
  2. Abbreviations: SAR, systemic immune-inflammatory index to ALB (SII/ALB) ratio; SII, systemic immune-inflammatory index; ALB, albumin; BMD, bone mineral density; MOF, major osteoporotic fracture; HF, hip fracture; LS, lumbar spine; FN, femoral neck; TH, total hip; DPN, diabetic peripheral neuropathy; PVD, peripheral vascular disease; BMI, body mass index; FBG, fasting blood glucose; HbA1c, glycated hemoglobin; Hb, hemoglobin; TSH, thyrotropin; FT3, free triiodothyronine; FT4, free thyroxine; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Cr, creatinine; UA, uric acid; Ca, calcium; 25(OH) D, 25-hydroxyvitamin D; WBC, white blood cell; Neut, neutrophils; Plt, platelets; Lym, lymphocyte; ALB, albumin