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Table 2 The characteristics of meibomian gland structure and function of included patients

From: Predictive modeling of graves’ orbitopathy activity based on meibomian glands analysis using in vivo confocal microscopy

Variable

Total

(N = 90 eyes)

Inactive group

(N = 49 eyes)

Active group

(N = 41 eyes)

P-value

MOA

1672.00

(1153.00 ~ 2444.75)

1699.00

(1310.00 ~ 2694.00)

1643.00

(1104.00 ~ 2170.00)

0.630*

MAD

85.51 ± 35.35

93.59 ± 39.09

75.85 ± 27.78

0.028

MALD

116.91 ± 28.99

119.31 ± 27.72

114.05 ± 30.53

0.267

MASD

41.59(31.85 ~ 54.69)

42.45(34.54 ~ 54.71)

39.12(29.78 ~ 54.56)

0.598*

MAI

   

0.012#

 0

1(1.11%)

1(2.04%)

0(0.00%)

 

 1

53(58.89%)

34(69.39%)

19(46.34%)

 

 2

32(35.56%)

14(28.57%)

18(43.90%)

 

 3

4(4.44%)

0(0.00%)

4(9.76%)

 

MSR

   

< 0.001#

 0

1(1.11%)

1(2.04%)

0(0.00%)

 

 1

49(54.44%)

17(34.69%)

32(78.05%)

 

 2

32(35.56%)

23(46.94%)

9(21.95%)

 

 3

8(8.89%)

8(16.33%)

0(0.00%)

 

AWI

   

< 0.001#

 0

12(13.33%)

12(24.49%)

0(0.00%)

 

 1

44(48.89%)

31(63.27%)

13(31.71%)

 

 2

22(24.44%)

6(12.24%)

16(39.02%)

 

 3

12(13.33%)

0(0.00%)

12(29.27%)

 

API

   

< 0.001#

 0

10(11.11%)

10(20.41%)

0(0.00%)

 

 1

37(41.11%)

28(57.14%)

9(21.95%)

 

 2

31(34.44%)

11(22.45%)

20(48.78%)

 

 3

12(13.33%)

0(0.00%)

12(29.27%)

 

MF

   

0.005#

 0

25(27.78%)

7(14.29%)

18(43.90%)

 

 1

56(62.22%)

37(75.51%)

19(46.34%)

 

 2

9(10.00%)

5(10.20%)

4(9.76%)

 
  1. MOA = Meibomian gland orifice area; MAD = Meibomian gland acinar density; MALD = Meibomian gland acinar longest diameter; MASD = Meibomian gland acinar shortest diameter; MAI = Meibomian gland acinar irregularity; MSR = Meibum secretion reflectivity; AWI = Acinar wall inhomogeneity; API = Acinar periglandular interstices inhomogeneity; MF = Severity of Meibomian gland fibrosis; P-values are for comparisons between the inactive phase of graves’ orbitopathy(GO) and the active phase of GO. Data is presented as medians (Q1 ~ Q3), means (± standard deviation), or n (%). Statistical analyses were performed using the following tests: * Mann-Whitney U test; † independent samples t-test; # chi-square test