Fig. 2

Heatmap of Spearman’s correlation between liver function and hormonal parameters. Warm colors indicate a positive correlation, in which the expression levels of liver function and hormonal tend to increase or decrease simultaneously. Cool colors represent a negative correlation, meaning that when the expression level of liver function increases, the level of hormonal decreases. The varying intensities of color reflect different degrees of correlation, with lighter shades representing weaker correlations and deeper shades indicating stronger correlations. The correlation coefficients range from − 1 to 1, with red near 1 indicating a very strong positive correlation and blue near − 1 indicating a very strong negative correlation. The numbers in the circle represent the correlation coefficient between liver function and hormonal. The asterisk indicates the P-value is less than 0.05, showing the statistical significance of the correlation. ALT = alanine aminotransferase, AST = aspartate aminotransferase, Copper = serum copper level, HFi = hepatic fibrosis index, LH = luteinizing hormone, FSH = follicle-stimulating hormone, E2 = estradiol