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Table 4 The main clinical and imaging features of the 40 WD patients comorbid with PCOS

From: Wilson disease combined with polycystic ovary syndrome–clinical features, treatment, and outcome in Chinese patients

Clinical feature

Total (n = 40)

Adolescent group (n = 18)

Reproductive age group

(n = 22)

p

Normal level group(n = 18)

Elevated level group(n = 22)

p

Neurologic

32(80%)

14(77.8%)

18(81.8%)

1.000

14(77.8%)

18(81.8%)

1.000

Hepatic

40(100%)

18(100%)

22(100%)

-

18(100%)

22(100%)

-

Psychiatric

8(20%)

5(27.8%)

3(13.6%)

0.430

3(16.7%)

5(22.7%)

0.709

Irregular menstruation

40(100%)

18(100%)

22(100%)

-

18(100%)

22(100%)

-

Hyperandrogenism

20(50%)

13(72.2%)

7(31.8%)

0.025

9(50%)

11(50%)

1.000

Polycystic ovarian morphology

40(100%)

18(100%)

22(100%)

-

11(100%)

15(100%)

-

Liver cirrhosis

36(90%)

15(83.3%)

21(95.5%)

0.310

15(83.3%)

21(95.5%)

0.310

Brain MRI abnormality

31(77.5%)

13(72.2%)

18(81.8%)

0.705

13(72.2%)

18(81.8%)

0.705

  1. Note: PCOS = polycystic ovary syndrome, WD = Wilson disease, MRI = magnetic resonance imaging. Data are expressed as n (%) or median (range) values. An ultrasound examination of the abdomen and ovary confirmed cirrhosis and polycystic ovary morphology, respectively