Hyperostosis frontalis interna and association of disease control with frontal bone thickness in acromegaly

BMC Endocrine Disorders

Table 4 Comparison of changes in bone measurements according to presence of HFI and disease control for at least last-year

	Group 1 HFI absent (n = 23)	Group 2 HFI present (n = 29)	pDifference (Group1-2)	Controlled (n = 36)	Uncontrolled (n = 16)	pDifference (Controlled-Uncontrolled)	Total (n = 52)
	Median(min.-max.)/ p value		pDifference (Group1-2)	Median(min.-max.)/ p value		pDifference (Controlled-Uncontrolled)	Median(min.-max.)/ p value
FBT^change	-0.10(-1.80–1.80)/ 0.637	1.10(-1.50–3.10)/<0.001	< 0.001	0.50(-1.80–3.00)/0.012	0.70(-0.90–3.10)/0.031	0.648	0.50(-1.80–3.10)/0.001
PBT^change	0.30(-2.30–3.3)/0.115	1.00(-3.00 - 3.20)/0.008	0.039	0.35(-3.00–3.30)/0.125	1.05(-0.80–3.20)/0.003	0.083	0.50(-3.00–3.30)/0.003
OBT^change	0.20(-2.90–2.20)/0.338	0.50(-1.40–3.50)/0.008	0.310	0.55(-2.90–3.50)/0.007	0.25(-1.40–1.70)/0.438	0.279	0.45(-2.90–3.50)/0.008

HFI: hyperostosis frontalis interna FBT: Frontal bone thickness PBT: Parietal bone thickness OBT: Occipital bone thickness

ISSN: 1472-6823