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Table 1 Patient characteristics before bariatric surgery, at weight nadir, at initiation, 6 and 12 months of GLP1-RA treatment

From: Efficacy of 12 months therapy with glucagon-like peptide-1 receptor agonists liraglutide and semaglutide on weight regain after bariatric surgery: a real-world retrospective observational study

Characteristics

 

Pre-surgery

 

Post-surgery weight nadir

 

GLP1-RA initiation

 

6 months treatment

 

12 months treatment

Age, yrs

 

43.0 (39.8, 52.5)

 

44.5 (41.0, 53.8)

 

50.0 (45.5, 58.5)

 

51.0 (46.0, 61.0)

 

51.5 (46.5, 59.5)

Time after BS, mo

 

-

 

17.0 (12.0, 25.3)

 

74.5 (51.0, 108.3)

 

77.0 (51.0, 108.0)

 

86.5 (65.0, 121.0)

Weight, kg

 

115.0 (106.5, 127.1)

 

80.9 (74.0, 89.2)

 

92.0 (82.5, 104.6)

 

81.6 (75.7, 94.4)

 

80.3 (73.5, 92.5)

BMI, kg/m2

 

41.8 (39.6, 47.1)

 

29.2 (26.5, 32.2)

 

32.6 (30.3, 38.9)

 

30.7 (28.5, 35.6)

 

29.3 (27.1, 34.1)

T2D, n (%)

 

10 (25.0)

 

5 (12.5)

 

9 (22.5)

 

8 (24.2) c

 

9 (22.5)

HbA1c, n (%)a

 

7.4 (7.0, 8.1)

 

6.8 (6.5, 7.1) b

 

7.1 (6.6, 7.7) b

 

6.3 (6.3, 6.5) d

 

5.9 (5.6, 6.3) d

OAD, noa

 

-

 

1.0 (1.0, 2.0)

 

1.0 (1.0, 2.0)

 

1.0 (1.0, 1.3)

 

1.0 (1.0, 1.5)

Insulin, n (%)a

 

5 (12.5)

 

0

 

1 (11.1)

 

1 (12.5)

 

0

Dyslipidaemia, n (%)

 

6 (15.0)

 

5 (12.5)

 

8 (20.0)

 

7 (21.2)

 

8 (20.0)

Hypertension, n (%)

 

17 (42.5)

 

6 (15.0)

 

6 (15.0)

 

6 (18.2)

 

7 (17.5)

  1. If not otherwise specified data are median values with interquartile range in brackets. Data are based on 40 patients, except at 6 months treatment (n = 33)
  2. BMI, body mass index; BS, bariatric surgery; HbA1c, glycated haemoglobin A1c; mo, months; No, number of; OAD, oral antidiabetic drugs; T2D, type 2 diabetes; yrs, years; a In patients with T2D. b information missing in one patient c information missing for seven patients d information missing in three patients