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Table 4 Classification of causes of drug-related problems with Levothyroxine

From: Evaluation of the clinical pharmacist’s effect on achieving treatment goals in patients with hypothyroidism: a randomized controlled trial

Classification Divisions

Pre (First visit)

Post (Second visit)

CG, n (%)

IG, n (%)

p

CG, n (%)

IG, n (%)

p

The Causes (including possible causes for potential problems)

      

1. Drug selection

8 (15.3)

21 (31.8)

 

8 (15.3)

0 (0)

 

 C1.3 Inappropriate combination of drugs or drugs and herbal medications

8 (15.3)

21 (31.8)

< 0.001

8 (15.3)

0 (0)

0.016

7. Patient related

44 (84.6)

45 (68.1)

 

44 (84.6)

24 (100)

 

 C7.5 Patient takes food that interacts

 C7.7 Inappropriate timing or dosing intervals

36 (69.3)

8 (15.3)

24 (36.3)

21 (31.8)

0.740

< 0.001

36 (69.3)

8 (15.3)

24 (100)

0 (0)

0.740

0.016

Total DRP (n = 118)

52 (100)

66 (100)

< 0.001

52 (100)

24 (100)

0.053

  1. C: Cause, CG: Control group, IG: Intervention group