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Table 4 Mediating effect between CRP and TyG

From: Application of the C-reactive protein-triglyceride glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study

Intermediate variable

CRP and TyG Association

Proportion mediated

Total HR(95%)

Direct HR(95%)

Model 1

   

CRP

0.087 (0.071,0103)

0.087 (0.071,0.103)

0%

TyG

0.003 (0.001,0.004)

0.003 (0.001,0.004)

0%

Model 2

   

CRP

0.087 (0.071,0103)

0.087 (0.071,0103)

0%

TyG

0.002 (0.001,0.004)

0.002 (0.001,0.004)

0%

Model 3

   

CRP

0.083 (0.067,0.099)

0.083 (0.067,0.099)

0%

TyG

0.002 (0.001,0.004)

0.002 (0.001,0.004)

0%

Model 4

   

CRP

0.059 (0.039,0.078)

0.060 (0.040,0.079)

0%

TyG

0.002 (0.001,0.003)

0.002 (0.001,0.004)

0%

  1. Model 1: unadjusted
  2. Model 2: adjusted for age and gender
  3. Model 3: adjusted for age, gender, marital status, residence, smoking and drinking status, education level and WHtR
  4. Model 4: plus hypertension, dyslipidemia and cardiovascular disease
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BMC Endocrine Disorders

ISSN: 1472-6823

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