Predictive value of growth hormone and insulin-like growth factor-1 axis for gestational diabetes mellitus: a prospective cohort study

Table 2 Biochemical characteristics of the study population(N = 241)

Characteristic	GDM(n = 113)	Non-GDM(n = 128)	t /χ²	P _value
FBG	4.96 ± 0.46	4.48 ± 0.30	-9.680	<0.001
OGTT 1hPG (mmol/L)	9.05 ± 1.71	6.98 ± 1.14	-10.877	<0.001
OGTT 2hPG (mmol/L)	8.36 ± 1.22	6.50 ± 0.94	-13.125	<0.001
Fasting insulin	21.98 ± 14.77	21.51 ± 12.04	0.278	0.781
HOMA-IR	4.55(3.54,4.55)	3.61(2.95,3.61)	-2.809	0.005
AUC _Glucose	15.71 ± 2.03	12.47 ± 1.41	-14.206	<0.001
IGF-1	7.33 ± 6.09	3.66 ± 3.44	-5.658	<0.001
GH	0.60 ± 0 0.73	0.91 ± 1.33	2.278	0.024

Continuous data are expressed as median (P25, P75) or mean ± SD
FPG fasting plasma glucose, OGTT oral glucose tolerance test, 1hPG 1-h plasma glucose, 2hPG 2-h plasma glucose, HOMA-IR homeostasis model assessment of insulin resistance, IGF insulin-like growth factor, GH growth hormone

ISSN: 1472-6823